Many complex brain development disorders are grouped under the general terms of autism and autism spectrum disorder (ASD). These disorder’s symptoms are characterized along a spectrum. Diagnostic markers include difficulties with social interaction, motor coordination, attention, verbal and nonverbal communication, and repetitive behaviors. ASD is related to intellectual disabilities, difficulties with motor skill coordination, difficulty focusing attention and physical health issues like gastrointestinal and sleep disturbances.
The roots of autism appear to be in early brain development but most signs and symptoms begin to present between ages 2 and 3.
Recent research finds that some autistic children may not adequately metabolize glutathione. Their inability to get the full benefits of the glutathione results in reduced detoxification capacity creating chronic oxidative stress. When the brain is under increased oxidative stress, there are often functional consequences in oxidative protein, DNA damage, and chronic inflammatory response.
Studies of autistic children treated with a transdermal application of glutathione (directly through the skin) showed a significant increase of the participant’s glutathione levels and indicate that it can potentially improve the symptoms of autistic disorders.